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An altered gut microbiome leads to the pathogenesis of neurodegenerative diseases by modulating and activating microglial functions

The authors acknowledge the mass spectrometry technical research services from National Taiwan University (NTU) Consortia of Key Technologies

Concurrently, T3 upregulates L-type calcium channels while reducing buffering proteins such as calbindin, creating a vulnerability to excitotoxicity (9496)

The supernatant was then analyzed by reverse-phase HPLC (Agilent 1260 Infinity LC, USA) on a Welch XB-C18 column (5 m, 250 mm 4.6 mm) equipped with a fluorescence detector at the excitation and emission wavelengths of 365 and 440 nm, respectively [9]

For example, mutations in proto-oncogenes often lead to colorectal cancer [13, 14]