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In this context, differential tryptophan metabolism depending on astrocyte or microglia predominance determines the balance between tryptophan catabolites, such as neuroprotective kynurenic acid and pro-inflammatory quinolinic acid (27)

In the ADVATE routine prophylaxis clinical trial, 3 children aged 7 to 12 years of age and 5 IU/kg/hr for subjects 5 to 12 years of age

A new target for gold(I) compounds: Glutathione-S-transferase inhibition by auranofin

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While seizure types did not significantly differ between early- and late-onset LS, focal and generalized tonicclonic seizures were most common in late-onset cases (34, 36)