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Metallomics: Integrated Biometal Science , 16
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For example, the antioxidant response factor NRF2, a bZIP transcription factor that heterodimerizes with small Maf proteins to bind to the AREs, can be targeted by a chimeric molecule termed 'ARE-PROTAC', which successfully induced simultaneous degradation of the NRF2-MafG complex and synergistically suppressed Nrf2 signaling (229)
Tea tree oil, which must be diluted before use, has been found to kill microscopic mites that can cause rosacea inflammation
GSH Concentration = Total Glutathione Concentration - [GSSG Concentration] x 2 *One molecule of GSSG (oxidized glutathione) is equivalent to two molecules of GSH (reduced glutathione)
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