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Ingestion of monosodium glutamate (MSG) in adult male rats reduces sperm count, testosterone, and disrupts testicular histology

MOTS-c activates AMPK (AMP-activated protein kinase), the master metabolic switch that signals cells to burn fat when energy is low

It facilitates the conversion of T4 to T3 through deiodinases (DIO1/DIO2) (3336)

An excretory function for the Escherichia coli outer membrane pore TolC: upregulation of marA and soxS transcription and rob activity due to metabolites accumulated in tolC mutants