Effective and at the right price point Effective with no negative side effects
Preventing symptoms and flares are the goal for daily quality of life and to avoid, or delay, surgical intervention
It appears to do this through several mechanisms including upregulation of growth factors involved in mucosal repair, reduction of inflammatory mediators, and support of gut barrier integrity
It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile
AOD 9604 is a synthetic 16-amino-acid fragment of human growth hormone (residues 176191), developed for studying fat and energy metabolism
