Moreover, the extrasynaptic copper concentration has been estimated to be in the nanomolar range based on the cellular and network excitability produced by bath-applied copper in the CA1 area of the rat hippocampal slice [244]
Adjuvant nivolumab plus chemotherapy versus placebo plus chemotherapy for stage III gastric or gastro-oesophageal junction cancer after gastrectomy with D2 or more extensive lymph-node dissection (ATTRACTION-5): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial
The most common side effects, reported in at least 5% of people being treated with Ozempic in clinical trials of the drug, were: nausea vomiting diarrhea abdominal pain constipation These side effects were typically mild and became less bothersome with time
2021;374:n1448
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