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when using a 1.5-mm dermaroller, there should be at least a 3-week gap between sittings and it takes approximately 36 months after treatment to see final results, to allow for collagen deposition [12]

doi: 10.2337/diabetes.52.11.2666

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[4] Our primer on what tirzepatide (Mounjaro/Zepbound) is and how it works and the deeper explainer on how tirzepatide influences incretin pathways lay out the receptor pharmacology

IDO activation can reduce tryptophan and increase toxic metabolites of the kynurenine pathway, which increases glial activation, neuroinflammation, toxicity, and neuronal death