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Research applications include NNMT pharmacology, methyltransferase signaling studies, enzymatic regulation investigations, and mechanistic evaluation of nicotinamide methylation pathways

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Clinical trials involving over 900 participants showed AOD-9604 to be well-tolerated with side effects indistinguishable from placebo in most studies

Nat Rev Drug Discov

When an intensive diet and exercise regime was incorporated into the study design, the peptides weight loss signal essentially disappeared versus the control group