Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics
doi: 10.1210/endo.142.8.8324
Important Considerations for Combining NAD+ and AOD9604 Despite the theoretical appeal, several crucial points must be considered when exploring the combination of NAD+ and AOD9604: Lack of Direct Combined Research: The most significant caveat is the current lack of extensive human clinical trials specifically investigating the combined effects of NAD+ precursors and AOD9604
However, it has been known for many years that B12 affects cognitive function, and B12 shots have long been used as an effective treatment in battling dementia and other cognitive disorders
It is common to do the injection using a thin, blunt tube called a cannula to make the treatment safe, more comfortable and limit the downtime