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Subcutaneous injections cannot deliver enough red methyl-B12 fast enough to be cleared by the kidney and show red in the urine unless the volumes are huge, significantly greater than any that I commonly use

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MOTS-c is a short peptide (16 amino acids), which makes it relatively resistant to the enzymatic degradation that degrades larger peptides, but also means that reconstitution technique and storage conditions matter considerably

While anyone can benefit from healthy B12 levels, certain groups are more likely to experience deficiencies and may see greater advantages from supplementation: Vegans and vegetarians: B12 is primarily found in animal products, making supplementation critical for those on plant-based diets

Stronger bones A B12 deficiency can lead to osteoporosis, brittle bones, and fractures