The expression of ER has been enriched in brain areas related to sexual behavior, such as the hypothalamus, while the expression of ER is more broadly expressed throughout the brain [for review about ER effects on neurodevelopment and its effects on behavior, see (78)]
Release profiles for the microspheres are achieved by modifying polymer and/or process conditions, with initial release or burst of the auris therapeutic agent also available
Intracellular GSH concentrations range from 0.5 to 10 mM in mammalian cells, with over 90% maintained in the reduced form under physiological conditions
Free radicals are unstable molecules that occur naturally but that also enter our bodies through toxins in food, air, water, and even medications
Variability in differentiation protocols and a lack of standardized benchmarks make it difficult to identify the most functionally matured and relevant stages of organoid development