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Unlike most peptides, which bind to a specific GPCR or tyrosine kinase, AOD-9604 acts via several indirect pathways with a predominance of effects on adipocytes (fat cells)

This temporal proximity means that metabolic perturbations are often detectable at lower drug concentrations and earlier time points than proteomic or transcriptomic changes making untargeted metabolomics a sensitive first-pass MoA screen

10.1111/j.1399-3054.1997.tb04779.x 34 FinkemeierI.GoodmanM.LamkemeyerP.KandlbinderA.SweetloveL

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Important Notice: GHK-Cu is intended for laboratory research purposes only