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In mice, hepatocyte-specific knockdown of Cyp51a1 impairs cholesterol biosynthesis, leading to hepatomegaly, oval cell hyperplasia, fibrosis, and inflammation

Its design supports multiple withdrawals from each vial, providing flexibility and efficiency for subcutaneous or intramuscular administration

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Although definitive causality could not be confirmed in the remaining cases, the audiometric patterns suggest noise-induced damage

Nevertheless, by integrating evidence from both Western medicine and TCM (20102025), this work proposes a pathogenesismechanismindicatorprescription framework that provides a foundation and direction for future systematic reviews and meta-analyses conducted under PRISMA guidelines