In STEP-1 (Wilding et al., NEJM 2021), 68 weeks of once-weekly 2.4 mg semaglutide plus lifestyle intervention produced a mean body-weight reduction of about 15%, versus about 2.4% with placebo a large, clinically meaningful, well-replicated effect
It also helps maintain healthy skin and aids in reducing tiredness and fatigue
PPAR, peroxisome proliferatoractivated receptor
Killing off the bacteria is helpful in clearing up breakouts, but without treating the overactive oil glands, this treatment usually doesnt produce the kind of long-lasting results patients are looking for
These trials are of low quality, and as such, use in widespread clinical practice is premature