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Heartburnretrosternal burning that ascends toward the neck Acid regurgitationthe unpleasant return of gastric contents to the pharynx The cardinal symptoms of GERD are heartburn (defined as retrosternal burning ascending toward the neck) and acid regurgitation (the unpleasant return of sour or bitter gastric contents to the pharynx)

In experimental contexts, Epithalon is explored for its influence on cellular longevity pathways, melatonin regulation, and genomic stability mechanisms

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This activation leads to the stimulation of the VEGFR2-Akt-eNOS signaling pathway, enhancing endothelial tube formation and blood flow recovery in ischemic tissues

Ultrasonography of the abdomen shows a liver mass