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and subsequent investigators has characterised GHK-Cu as a potent activator of wound-healing cascades, upregulating transforming growth factor- (TGF-) and suppressing inflammatory mediators such as TNF- and IL-6 in pre-clinical models

[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Yun K.U., Ryu C.S., Oh J.M., Kim C.H., Lee K.S., Lee C.-H., Lee H.-S., Kim B.-H., Kim S.K

Response Susceptibility Chem

doi: 10.1089/ham.2012.1052

The search combined the keywords: chronic kidney disease, CKD pathophysiology, nephroprotective plant extracts and phytochemicals, plant extract or phytoconstituents loaded nanoformulations, and novel herbal drug delivery. The review includes journal articles, referred books, dissertations, and studies published in English between 2006 and 2024