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Week 1: Dose: 50mcg Frequency: Once, on a night when you can sleep in the next morning Timing: 2-3 hours before intended sleep Purpose: Assess basic tolerance and response Week 2: Dose: 75-100mcg Frequency: 2-3 times during the week Timing: 1-2 hours before bed Purpose: Establish baseline effective dose During this assessment phase, track sleep quality subjectively and, if possible, with a wearable device that measures sleep stages

[DOI] [PubMed] [Google Scholar] 213.Sargeant TD, Aparicio C, Goldberger JE, Cui H, Stupp SI

(September 1984)

Animal Toxicology Limitations Some animal experiments did not report obvious toxicity or increased total tumour incidence

It directly signals your body to upregulate the production of both collagen AND elastin