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Methods: 2100 adults within 24 hours of stroke onset, moderate to severe neurological impairment (NIHSS10) or dysphagia and NIHSS6, without pneumonia at screening, contraindications to metoclopramide, pregnancy, and life-limiting comorbidities will be recruited from 60 or more UK hospitals

For someone already managing endo belly, this worsening period can feel like a disease flare

Its often more cost-effective when doing long-term trials