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33176370 Der-Nigoghossian C, Tesoro EP, Strein M, Brophy GM

Numerous reports showed that the induction of antioxidant defense systems is beneficial to oxidative damage and inflammation response prevention, thereby, alleviating metabolic syndrome ( CHI had a protective effect on liver injury, as reflected by the reduced levels of AST in serum (Figures 2E, F, 3E, 5HI) in murine with glucose or/and lipid dysmetabolism induced by ALX or high-fat diet

Moreover, consuming a HFD increased protein S -glutathionylation (protein-SSG formation) in the liver

GHK-Cus mechanism depends on cumulative tissue signaling rather than peak concentration

doi:10.1016/j.taap.2011.12.018 [7] Marques AC, Mariana M, Cairrao E