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Acknowledgements This work was supported by Chang Gung Memorial Hospital [CMRPG391311, CMRPG3A1131, CMRPG3H0611 and Grants CIRPD1D0071-3

Rare side effects include: hypokalemia, muscle weakness, allergic reaction symptoms such as shortness of breath or hives

In our model, our oral doses are deposited in the gut compartment and then removed and put into the liver with linear kinetics

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