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VMAT2 mediates the sequestration of monoamine neurotransmitters, including dopamine and norepinephrine (NE), into synaptic vesicles

Clinical evaluation: For Class C and Class D applications, a clinical evaluation report (CER) must be submitted to HSA

Preferred sites: lower abdomen (2 inches either side of the navel), outer thigh, love-handle area

Currently, large-scale production of the pigments is achieved through extraction from plant raw materials with high contents of stable anthocyanins ( 1 ), for example, purple sweet potato, black carrot or red cabbage 5 , despite the associated issues of sustainability and supply

If histamine-type welts recur, a different diluent is a formulation-specific decision for the prescriber or pharmacy