Caspases can serve different roles in the apoptotic cascade: some act as initiators (e.g., caspase-8, caspase-9), while others function as effectors (e.g., caspase-3, -6, -7), ultimately executing apoptosis by cleaving essential cellular proteins [159]
NRF2 is a major target of ARF in p53-Independent tumor suppression
When blood pressure drops, less blood and oxygen may reach the brain, leading to feelings of lightheadedness or dizziness
33 Lutein accumulates in green leafy vegetables, and zeaxanthin accumulates in spinach, while lycopene is abundant in tomatoes, watermelon, guava, pink grapefruit, and blood oranges
doi: 10.1001/jama.1978.03280280034020 110 CosgroveKTKuplickiRSavitzJBurrowsKSimmonsWKKhalsaSSet al