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We reviewed Sikiric 1993-2026 (Zagreb, over 150 BPC-157 papers), the AJSM 2026 systematic review (35 preclinical studies), the 2026 pilot PK study in two healthy subjects, and the February 2026 STAT review

Funding This work was supported by grants from Zhejiang Clinical Research Center for Mental Disorders (grant number SLC202303 to X.L.)

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Besides the interleukin family, other genes related to the skin inflammatory mechanism were also upregulated