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found in every cell, its primary function is to aid in the conversion of glucose into energy

J Biol Chem (1986) 261:225663

The mutated protein mHtt is progressively accumulated in cells, with a particularly high concentration in the brain

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By initiating the breakdown of L-tyrosine in the proximal region of the small intestine with consequent reduction of the quantity reaching the colon and by competing with the native gut microbiota in the colon implicated in p-cresol generation from L-tyrosine, the therapeutic strain exerts its activity in CKD patients