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Treatments Appropriate fluid therapy, correction of electrolyte abnormalities, prompt diuresis, and monitoring of renal function are particularly important to prevent platinum-based renal injury (53).There is currently no effective way to reverse AKI or tubular dysfunction, and treatment of renal toxic manifestations is primarily supportive with an aim to relieve symptoms

Comprehensive bloodwork covering hormonal baseline, thyroid, metabolic markers including fasting insulin, inflammatory markers, and IGF-1

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