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The result of this study showed a statistically significant difference between GSH levels of the Groups A and B

This makes the monotherapy regression coefficient less robust than the combination finding Heterogeneity in protocols: The included studies used different needle depths (0.52.5 mm), frequencies (weekly to monthly), devices (dermaroller, dermapen, fractional radiofrequency), and treatment durations, which adds variability to the pooled analysis Primarily male populations: Most included studies focused on male androgenetic alopecia

Results vary, and consistency often plays a role in noticeable changes

PMID 18177777

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