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For many patients, this combination helps reduce abdominal discomfort, improve nutrient absorption, and maintain remission longer between flare-ups

doi: 10.1016/S2213-8587(19)30068-3 [DOI] [PubMed] [Google Scholar] 15.Look AHEAD Research Group, Wing RR, Bolin P, et al

Each has documented limitations: NSAIDs: Reduce inflammation short-term but inhibit prostaglandin pathways needed for tissue repair

Initial Loading Dose: At first, people get 1000 mcg every week for 4-8 weeks

The phase IIb clinical trial studying danuglipron twice daily in participants with obesity had over 50% of patients discontinue treatment in comparison to about 40% with placebo