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A modified FOXO4-p53 interfering peptide causes p53 nuclear exclusion, which can: Selectively induce apoptosis in senescent cells in vitro and in vivo Neutralize phenotypical and liver chemotoxicity by Doxorubicin Restore fitness, hair density and renal function in fast and naturally aged mice Acknowledgments We thank Felicity Chandler for assistance with IHC experiments, Anne Drabbe and David Brouwer for assistance with in vivo experiments, Yanto Ridwan for assistance with CT and IVIS imaging, Yvette van Loon for genotyping of the mice, Martin Viertler for initial NMR experiments, Boudewijn Burgering for fruitful discussions and Petra de Keizer-Burger for critical reading of the manuscript
BPC-157 is a synthetic peptide made up of 15 amino acids, derived from a naturally occurring compound in human gastric juice called Body Protection Compound (BPC)
This provides LAZAR with the advantage of providing toxicological predictions for endpoints that provide sufficient empirical information
When you choose this blended peptide product, you ensure verified purity, secure shipping, and transparent pricing tailored to your laboratory needs
