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It is known that in DM, the NO bioavailability is reduced through modulation of the endothelial nitric oxide synthase (eNOS) activity and oxidative stress [82]

Synthesis of 3-(4-(pyridin-2-yldiazenyl)phenoxy)propan-1-ol (compound 2) The 3-(4-(pyridin-2-yldiazenyl)phenoxy)propan-1-ol was synthetized using a similar procedure as previously reported 46

Metformin and intermittent fasting mitigate high fat-fructose diet-induced liver and skeletal muscle injury through upregulation of mitophagy genes in rats

Among the diverse array of contaminants, organic pollutantssuch as industrial dyes, pharmaceutical waste, contaminants of emerging concern (CECs), and harmful biological agentspose severe risks to ecosystems and human health 11,25