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To investigate this further, the researchers gave older mice a single dose of the common nutritional supplement L-carnitine, which is known to increase levels of acylcarnitines

Sex differences on the response to antidepressants and psychobiotics following early life stress in rats

Cryan et al., 2019), tend to be both accompanied and preceded by not only mitochondrial dysfunction but also dysbiosis and intestinal disease (see also Vogt et al., 2017