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These transcriptional effects of SREBP include (but are not limited to) increased expression of glucokinase (encoded by GCK), liver pyruvate kinase (encoded by PKLR), lipoprotein lipase (encoded by LPL), fatty acid synthase (encoded by FASN), and acetyl-CoA carboxylase 1 (encoded by ACACA), and decreased expression of glucose 6-phosphatase (encoded by the G6PC gene), fructose 1,6-bisphosphatase (encoded by FBP1), and mitochondrial phosphoenolpyruvate carboxykinase (encoded by PCK2)

Any mention of peptides, their functions, or potential applications is intended solely to support general wellness education and informed discussion

Treating rosacea requires a multifaceted approach to calm irritated skin, reduce inflammation, and minimise triggers

E.EllingerT.StraubJ.et al

Sep 25 2014;371(13):1218-1227