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647 In addition, resveratrol can also trigger the AMPK/ SIRT1/PGC-1 pathway to inhibit ROS-induced apoptosis in HG-treated retinal capillary endothelial cells

Selection of candidate mutants Upon massively parallel sequencing of our samples, we determined the enrichment and depletion of each variant within the treatment populations relative to the untreated control population

Glutathione plays a crucial role in combating oxidative stress and neuroinflammation, which are key factors in the progression of these disorders