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It exhibits a high affinity for the muscle enzyme, carnitine acyl transferase, and as such readily converts into propionyl-CoA and free carnitine

Histology results Before the initiation of therapy, at 10 min after injury induction, a large hemorrhagic zone was present over the lateral and posterior white columns in all of the rats, but there were no changes in the gray matter

Many of the highly significant pathways in Figure 8 are related to energy metabolism, including amino acid metabolism, sugars, citric acid cycle, pyruvate metabolism, and glycolysis. Such pathways are familiar from the metabolomics ME/CFS literature (23, 24), but their evolution through the recovery period is probably novel

One in particular to look up is ProdromeNeuro

Then, at some point, due to increasing number of crystals or other inciting factor, the matches are struck and the inflammation begins