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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

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Furthermore, more focus and conciseness would be required in ROS research

In the elderly, hypothyroidism is associated with accelerated cognitive decline and an increased risk of Alzheimer's disease, raising the possibility that impaired thyroid signaling may act as a modifiable risk factor for dementia (83)

Abstract Although erythropoietin ameliorates experimental type 2 diabetes with neuropathy, serious side effects limit its potential clinical use