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Yes-cholestyramine, sucralfate, proton-pump inhibitors, and certain estrogen formulations can reduce bioavailability or alter protein binding

Takabatake S, Ohtsuka S, Sugawara T, Hatano N, Kanayama N, Magari M, et al

[7] Because serious glutathione depletion can occur under conditions of trauma and stress, maintenance of adequate glutathione levels may enhance immunocompetence and thus improve your ability to recover from illness or physical stress

I often liken glutathione to a hotel cleaner, Glutathina it cleans all your rooms and gets rid of dust, dirt, polishes, and hoovers

Looking again at the fasting mimicking diet, we know that people can still experience many fasting benefits even with some (minimal) protein intake