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wrinkles begin to appear because of the decline in collagen and elastin fibers in the dermal layer [2, 10, 14, 20]

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ROS play an important role in microbial decontamination either directly by inducing oxidative stress or indirectly by promoting pathogen clearance through a number of non-oxidative mechanisms, including autophagy, T-cell responses, and pattern recognition receptor signaling 44

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Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial