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(A) The structure of hepatocyte growth factor (HGF) includes a -chain (69 kDa) of four Kringle domains and a -chain (43 kDa) consisting of a serine proteinase homology (SPH) domain linked by disulfide bonds
This could contribute to liver diseases such as cirrhosis , which involves liver scarring and loss of function
The peptides documented interaction with the nitric oxide pathway which plays a central role in vascular tone makes cardiovascular effects a logical area of investigation
[DOI] [PubMed] [Google Scholar] 918
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