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Its effective concentration ranges from the sub-nanomolar to nanomolar range, with 500 nM commonly used in vitro to ensure full TrkB activation

doi:10.1016/bs.pbr.2021.01.023

GLP-1 and GIP receptors are G-protein-coupled receptors expressed primarily in pancreatic beta cells, the hypothalamus, and the GI tract

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The Ferguson reflex for fetal ejection: Fetal stretch signals from the birth canal and uterine tissue activates spinal and vagal inputs to the brainstem including the solitary tract nucleus, which then sends a noradrenergic depolarizing input to hypothalamic oxytocin neurons