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Mice were then sacrificed 6 days after irradiation and small intestines were examined for morphologic changes and crypt cell apoptosis

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After treatment with 40100 M KL1, 100 M KL2, 40100 M inactive analogue KL7, 110 M BIX-01294 or 20 M BHA, infected cells were washed twice with 200 l PBS and incubated with 100 l of 2550 M Fl-B in PBS at 37 C for 30 min

The study was supported by the NCIs Patient-Derived Models of Cancer program, which promotes the development of animal models that more closely mirror how tumor cells behave in humans