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Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family

Unlike GHK-Cu, which occurs naturally in the human body and has broad skin research behind it, AHK-Cu was designed with hair biology in mind - particularly its potential to interact with the Wnt/-catenin signalling pathway involved in hair follicle cycling

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Insufficient, excessive or mistimed autophagic flux can shift selective autophagy from an adaptive quality control mechanism to a response that favours ferroptosis, senescence and maladaptive immune remodelling