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The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

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The 1:1 blend is expressed as one combined dose because the two move together

[DOI] [PubMed] [Google Scholar] 56.Li X, Yang Z, Zhang A, Wang T, Chen W