While TTR-V30M carriers in the Portuguese, Brazilian, and Japanese populations share a common ancestral origin, the same mutation in Sweden has arisen independently [8]
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doi: 10.1111/j.1526-4637.2009.00596.x
This metabolic safety profile expands the potential population who might safely use the peptide under medical supervision
FIGURE 1 To find out a specific mechanism, a comparison with the becaplermin (recombinant human plateletderived growth factor homodimer of B chains, PDGF-BB) was the focus of the two additional studies using excisional wounds in diabetic rats and mice (Figure 2) (Seveljevic-Jaran et al., 2006