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Under normal physiological conditions, HSP acts as a chaperone protein helping the protein folding (mainly unfolded, misfolded, and partially folded new peptide chains) and translocation into the endoplasmic reticulum lumen [86]
Of the eight GPxs, GPx4 is essential for life as the mice lacking it (knock out or KO) do not survive [1, 8, 9]
MnTCPP + monochloride, TCPP + monochloride, FeTCPP + monochloride, gallic acid and reduced glutathione were provided by J&K Scientific
[3] It is synthesized by attaching cysteine to the carboxyl group of the glutamate side chain with a gamma peptide linkage, and to glycine with a normal peptide bond