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The structure-based design of Mdm2/Mdmx-p53 inhibitors gets serious

Wrote the paper: CC, LL, and KL

Tailoring tumor vessels to optimize cancer therapy Going beyond anti-angiogenesis and vascular normalization, strategies that can alter vessel phenotype to optimize specific types of cancer therapy are quickly emerging

The condition differs from other forms of B12 deficiency because it stems from an autoimmune process attacking parietal cells rather than dietary insufficiency or malabsorption disorders