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Continue Reading Injecting B12 into fat results in slower absorption, which may mean less B12 is wasted

Typical loading phase protocols: Daily injections for the first week Weekly injections for the next 4-6 weeks This intense schedule quickly boosts B12 levels

Cost is worth considering

Sklamberg says these products could be viewed as unregulated drugs, though the volume of online retail makes it difficult for the FDA to go after every bad actor

By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways