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Sourander, Andre, et al

1,2,6,12 Dementia-like disease, including episodes of psychosis, is thought to be associated with more severe and chronic deficiency, although supporting evidence is poor

Just look at the history of people with ME (myalgic encephalomyelitis) or with Long-Covid, and how they have been ill-diagnosed and not well treated, and you realize how mediocre the specific evaluation of many people with unexplained symptoms may have been

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Only then can the cobalt atom be reduced from an oxidative state of +3 to the biologically active +1, forming methyl B12 in the cytosol, and adenosyl B12 in the mitochondria