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The formula is: Daily sublingual dose = (Weekly injectable dose x Injectable bioavailability) / (7 days x Sublingual bioavailability) Using 80% injectable and 30% sublingual bioavailability as the midpoint estimate: Daily sublingual = (Weekly injectable x 0.80) / (7 x 0.30) = Weekly injectable x 0.38 This means a 10 mg weekly injectable dose translates to approximately 3.8 mg daily sublingual

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Finally, eryptotic RBCs are engulfed and processed by Kupffer cells, the phagosome containing eryptotic RBCs merges with lysosomal vesicles, obtaining a complex called the erythrophagolysosome