When NAD+ levels are adequate, SIRT1 activity increases, promoting DNA repair, reducing inflammation, and enhancing stress resistance
This depletion can lead to anemia, and also an increased risk that their breastfed infants become vitamin deficient
Vitamin B12 helps make red blood cells, keeps nerves working, and aids in DNA creation
So, if you are eating a varied diet and do not have a laboratory-documented vitamin B12 deficiency, you do not need additional supplementation. However, she explains people who subscribe to strict vegan or vegetarian diets are much more likely to be at risk of vitamin B12 deficiency, and they should take supplemental B12, especially when pregnant or trying to become pregnant
Route/evidence mismatch: the pivotal mouse study tested subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) the oral capsule use that is actually sold and discussed commercially has not itself been directly tested in that published research
