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The multi-system nature of fibromyalgia, affecting sleep architecture, pain processing, immune function, and cognitive performance simultaneously, demands interventions capable of addressing multiple pathways rather than single targets

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On the other hand, the presence of Tm cells, the increase in the number of Th and Tc cells possibly resulted from the increased differentiation of Tn cells after treatment

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reported that GAD autoreactive CD8+ T cells derived from T1D PBMCs recognize CVB3 viral peptides (159)