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Some users cycle 16-24 weeks on, 4-8 weeks off

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For comparison, FDA-approved anti-obesity medications like semaglutide 2.4 mg (Wegovy) have cardiovascular outcomes data from the SELECT trial (N=17,604, median follow-up 39.8 months), which demonstrated a 20% reduction in major adverse cardiovascular events [6]

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Neither of these pathways overlap significantly with amylin signaling

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